2 March, 2015

Waklert

Waklert is a brand name alternative to Nuvigil, manufactured by Sun Pharma based in Mumbai, India, that contains the active ingredient Armodafinil. It's one of the most commonly used and safest psycho-stimulants which promotes wakefulness, improves mood of users and enhances cognitive ability by altering the action of certain natural chemicals (neurotransmitters) within the brain. Armodafinil is a precursor to Modafinil meaning that the body converts it into Modafinil but because of this, it takes longer for it to take effect.


What conditions are treated using this medication?

Waklert is medically approved and traditionally used for treating excessive daytime sleepiness caused by sleep apnea, shift work sleep disorder and narcolepsy. It is also regularly used off label to treat a wide range of conditions including jet lag, "atypical" depression, neurological fatigue, weight loss, Parkinson's disease and ADHD. University students routinely use it for it's cognitive enhancement effects and militaries from several countries around the world including the US military use it as an alternative to amphetamines. In 2009, the Canadian Medical Association Journal reported that Armodafinil is used by ISS (International Space Station) crew members due to it's vigilance enhancing effects allowing them to optimize their performance, regardless of how fatigued they feel. In the last four years alone, sales of Armodafinil have increased by 74% due to a number of factors including many senior executives such as Silicon Valley investor, Dave Asprey, going public about their daily use which they claim allows them to perform better with elevated mental clarity, focus, concentration and drive. A quick search of his name in YouTube will reveal countless videos of this colloquially named "bullet proof executive" plus many other people in professional capacities discussing their personal use of these study pills with the likes of CNN and ABC news.


Recommended dosage of Waklert:

The recommended dose of Waklert is 150 mg taken once a day in the morning or early afternoon with a glass of water except in the case of shift work sleep disorder where it should be taken approximately one hour before work.

Doses of up to 300 mg a day in a single dose or split into two doses of 150 mg have been well tolerated and whereas some people benefit from the increased dosage, others have reported no additional benefit beyond that of a single dose. Waklert is non addictive and the potential to suffer severe or even moderate adverse reactions is extremely low. Clinical trials involving high doses for extended periods indicate no long terms damage occurs and there are no recorded cases of overdose.


Are there any side effects associated with taking this drug?

Most people suffer no side effects from using Waklert but about 5% of users reported mild side effects including headache, nervousness, rhinitis, nausea, anxiety, insomnia, dizziness, back pain, stomach upset or diarrhea. Rare side effects include mental or mood changes (confusion, agitation, depression, hallucinations and abnormal thoughts), chest pain, fast/irregular/pounding heartbeat, signs of an infection (fever, persistent sore throat) and users should seek medical attention in any of these cases. A severe allergic reaction to the active ingredient is extremely rare but stop using it and seek immediate medical attention if after using Armodafinil, you notice a skin rash developing, blister/peeling skin, trouble breathing, severe dizziness, itching or swelling of the face, throat or tongue.


Contraindications and warnings:

If you plan on using Waklert, it is important to consult with a doctor beforehand if you have had any previous cardiovascular problems particularly when using other pharmaceutical stimulants. Individuals with a history of cardiac condition such as left ventricular hypertrophy and mitral valve prolapse should also consult a doctor before taking Armodafinil. Before using generic Nuvigil, consult with your doctor or a pharmacist regarding any prescription or non-prescription/herbal products you are using, especially medications for high blood pressure and/or "beta blockers" (e.g. metoprolol, atenolol, guanabenz, methyldopa, clonidine, prazosin) "blood thinners" (e.g. warfarin), stimulants or alternative study drugs (e.g. ritalin, adderall, dexedrine), "medications that affect liver enzymes" (e.g. rifamycins such as rifabutin/rifampin, antifungals such as itraconazole/ketoconazole, anti-seizure medications such as carbamazepine/phenobarbital).

The active ingredient, Armodafinil, may speed up or slow down the removal of other prescription medications from the body by affecting certain liver enzymes. The affected drugs include cyclosporine, propranolol, phenytoin, diazepam, theophylline, triazolam and certain antidepressants (e.g. clomipramine, desipramine, fluoxetine, fluvoxamine). Avoid taking MAO inhibitors (furazolidone, moclobemide, linezolid, isocarboxazid, phenelzine, tranylcypromine, selegiline, procarbazine) in the 2 weeks before, during, and after treatment. Please note this is only a brief summary of the warnings and contraindications associated with the use of Armodafinil and potential users should seek more details either from a qualified physician.